| ncRNA name | PEDF siRNA |
| ncRNA Category | siRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Mus musculus |
| Tissues/Cell_line | mouse Müller cells |
| Methods | siRNA transfection, Western blot, qRT-PCR, glutamate uptake assay, GPx activity assay |
| Expression pattern | associated |
| Functional description | Downregulation of PEDF expression by siRNA in Müller cells resulted in decreases in glutamate uptake, Kir4.1 and GLAST expression, and induced oxidative stress. |
| PubMed ID | 22266516 |
| Year | 2012 |
| Title | Effect of pigment epithelium-derived factor on glutamate uptake in retinal Muller cells under high-glucose conditions. |
| Drug-related ncRNA | NO |
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